Janine l. kwapis

Abstract. Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association.The NR2B subunit confers unique properties to the NMDAR and may differentially regulate these two fear memories.Ivana Maric 1, 2 Lorena López - Ferreras 2 Yashaswini Bhat 1 Mohammed Asker 2 Stina Börchers 1, 2 Lauren Bellfy 3, 4 Janine L. Kwapis 3, 4 Karolina P. Skibicka 1, 2, 4* 1 Department of Nutritional Sciences, College of Health and Human Development, The Pennsylvania State University, United StatesJanine L. Kwapis, Timothy J. Jarome, Nicole C. Ferrara, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 16 Scopus citations. Overview; Fingerprint; Abstract. Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work has shown ...Europe PMC is an archive of life sciences journal literature.Janine L. Kwapis: Conceptualization, Writing - original draft, Writing - review & editing, Supervision, Funding acquisition. Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.Destiny S. Wright, 1 Kasuni K. Bodinayake, 1 and Janine L. Kwapis 1, * Destiny S. Wright 1 Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, USAJanine L. Kwapis, PhD THE PAUL BERG EARLY CAREER PROFESSOR IN THE BIOLOGICAL SCIENCES; Assistant Professor of Biology. [email protected]. My research focuses on understanding the epigenetic and molecular basis of long-term memory. I'm particularly interested in understanding how these mechanisms are altered in the aging brain and how epigenetic ...Nicole C. Ferrara, 1 , 2 Janine L. Kwapis, 3 and Sydney Trask 4 , 5 , * Nicole C. Ferrara 1 Discipline of Physiology and Biophysics, Rosalind Franklin University, North Chicago, IL, United StatesAlaghband Y, Kwapis JL, López AJ, White AO, Aimiuwu OV, Al-Kachak A, Bodinayake KK, Oparaugo NC, Dang R, Astarabadi M, Matheos DP, Wood MA (2017) Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory.Kwapis JL, Jarome TJ, Gilmartin MR, Helmstetter FJ. Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. Neurobiol Learn Mem. 2012; 98:148–153. doi: 10.1016/j.nlm.2012.05.003. [PMC free article] [Google Scholar] The emphasis here is on the lines available as opposed to methods on how to develop transgenic mice, which has been discussed in detail previously (Doyle et al., 2012). Additionally, we will discuss other genetic tools available to neuroscientists, such as siRNAs, viral-mediated approaches, and variations of the CRISPR-Cas9 system.Research The Kwapis Lab studies the molecular and epigenetic mechanisms that underlie long-term memory formation, storage, and updating. We want to understand the mechanisms that underlie memory and identify how these mechanisms are dysregulated during aging, leading to age-related memory impairments.Jarome, Timothy J. ; Kwapis, Janine L. / Special issue "molecular mechanisms of memory formation and modification ...Jan 31, 2017 · Europe PMC is an archive of life sciences journal literature. Abstract In the laboratory, memory is typically studied as a de novo experience, in which a naïve animal is exposed to a discrete learning event that is markedly different from its past experiences...2020 Jan;45(2):337-346. doi: 10.1038/s41386-019-0438-0. Epub 2019 Jun 15. Authors. Janine L Kwapis , Yasaman Alaghband , Ashley A Keiser , Tri N Dong ...We finally asked whether HDAC3 serine 424 phosphorylation (ser424) that controls HDAC3 activity and histone acetylation (Kwapis et al, 2017) is able to regulate DRG outgrowth. We overexpressed phospho‐mimetic or phospho‐dead HDAC3 S424A or S424D mutant plasmids in cultured DRG cells, respectively.Kwapis, Janine L López, Alberto J et al. Publication Date 2017-11-01 DOI 10.1016/j.nlm.2017.09.001 Peer reviewed eScholarship.org Powered by the California Digital Library University of California. Distinct roles for the deacetylase domain of HDAC3 in theActivation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association.Janine L. Kwapis , Contributed equally to this work with: Craig T. Werner, Janine L. Kwapis Affiliation Department of Psychology, University of Wisconsin, Milwaukee, Wisconsin, United States of America ⨯ . Fred J. Helmstetter * E-mail: [email protected] is accompanied by cognitive deficits, including impairments in long-term memory formation. Understanding the molecular mechanisms that support preserved cognitive function in aged animals is a critical step toward identifying novel therapeutic targets that could improve memory in aging individuals. One potential mechanism is the Nr4a family of genes, a group of CREB-dependent nuclear ...Author links open overlay panel Alberto J. López a b c, Thekla J. Hemstedt a c, Yousheng Jia d, Philip H. Hwang a b c, Rianne R. Campbell a b c, Janine L. Kwapis a c, Andre O. White e, Om Chitnis a b c, Vanessa M. Scarfone f, Dina P. Matheos a b c, Gary Lynch b c d, Marcelo A. Wood a b cLauren Bellfy 1 2 , Chad W Smies 1 , Alicia R Bernhardt 1 , Kasuni K Bodinayake 1 , Aswathy Sebastian 2 , Emily M Stuart 1 , Destiny S Wright 1 , Chen-Yu Lo 1 , Shoko Murakami 1 , Hannah M Boyd 1 2 , Megan J von Abo 1 , Istvan Albert 2 3 , Janine L Kwapis 4 5Abstract. Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association.The NR2B subunit confers unique properties to the NMDAR and may differentially regulate these two fear memories.AU - Kwapis, Janine L. AU - Helmstetter, Fred J. PY - 2014/6 Y1 - 2014/6 N2 - Work on the long-term stability of memory has identified a potentially critical role for protein kinase Mzeta (PKMζ) in maintaining established memory.Author links open overlay panel Timothy J. Jarome 1, Nicole C. Ferrara 1, Janine L. Kwapis, Fred J. Helmstetter. Show more. Add to Mendeley. Share. ... of memory and blocks the effect of protein synthesis inhibitor anisomycin on memory reconsolidation (Jarome, Ferrara, Kwapis, & Helmstetter, 2016; Jarome et al., 2011; Lee et al., 2008a). The ...Janine Kwapis Page 2 • First Place Award for Oral Presentation, UCI ReMIND Emerging Scientists Symposium, UC Irvine 2015 • NIH T32 Institutional Training Grant Recipient, UCI MIND 2014-2016 • NIH F31 Predoctoral Ruth L. Kirschstein National Research Service Award (NRSA) – 3 year fellowship 2011-2013Europe PMC is an archive of life sciences journal literature.The retrosplenial cortex is involved in the formation of memory for context and trace fear conditioning Janine L. Kwapis1, Timothy J. Jarome2, Jonathan L. Lee, Fred J. Helmstetter Department of Psychology, University of Wisconsin–Milwaukee, 2441 E. HartfordJanine L. Kwapis, Timothy J. Jarome, Janet C. Schiff, and Fred J. Helmstetter; Learn. Mem. November 2011 18: 728-732; Published Online October 25, 2011, doi: 10.1101/lm.023945.111 . Abstract; Full Text; Full Text (PDF) Supplemental Material; RESEARCH. Select this article. Interaction between the basolateral amygdala and dorsal …Janine L. Kwapis, Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA; e-mail: [email protected]. Metrics and citations MetricsWelcome to the Kwapis Lab! We are located at the University Park campus of Pennsylvania State University in the department of Biology.Our lab is part of the Eberly College of Science, and we’re affiliated with the Huck Institutes of the Life Sciences.. We are interested in identifying the molecular and epigenetic mechanisms that support long-term memory …Bellfy, L.; Kwapis, J.L. Molecular Mechanisms of Reconsolidation-Dependent Memory Updating. Int. J. Mol. Sci. 2020 ... Janine Kwapis; Memory is not a stable record of experience, but instead is an ...AU - Kwapis, Janine L. N1 - Funding Information: This work was supported by the National Institutes of Health (grants R00AG056596 and R21AG068444) awarded to J.L.K.; the Whitehall Foundation (grant 2020-05-06 to J.L.K.); and was conducted while Janine Kwapis was a Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty awardee ... Janine L. Kwapis, Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA; e-mail: [email protected]. Metrics and citations Metrics. Journals metrics. This article was published in Journal of Biological Rhythms. VIEW ALL JOURNAL METRICS.In the laboratory, memory is typically studied as a de novo experience, in which a naïve animal is exposed to a discrete learning event that is markedly different from its past experiences. Most real...Janine Kwapis; Timothy J Jarome; Jonathan L. Lee; Fred J Helmstetter; The retrosplenial cortex (RSC) is known to play a role in the retrieval of context memory, but its involvement in memory ...Abstract In the laboratory, memory is typically studied as a de novo experience, in which a naïve animal is exposed to a discrete learning event that is markedly different from its past experiences...BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens André O. White, Enikö A. Kramár, Alberto J. López, Janine L. Kwapis, John Doan, David Saldana, M. Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P. Matheos and Marcelo A. Wood () ...For example, dominant-negative mutations in which a catalytically impaired mutant out-competes the endogenous gene, ultimately impairing that gene’s function, have been used to assess the importance of protein function for a variety of genes during synaptic plasticity and memory formation (Gao et al., 2015; Kang et al., 2001; Kwapis et al ...The circadian system influences many different biological processes, including memory performance. While the suprachiasmatic nucleus (SCN) functions as the brain's central pacemaker, satellite clocks have also been identified in other brain regions, such as the memory-relevant dorsal hippocampus. Although it is unclear how these satellite clocks contribute to brain function, one possibility ...Previous work from our lab (Kwapis et al., 2011, Kwapis et al., 2014, Kwapis et al., 2015) has demonstrated that a 6-trial trace fear conditioning protocol with a variable intertrial interval (ITI) of 240 ± 20 s produces approximately the same level of freezing as 4 trials of delay fear conditioning with a shorter ITI of 110 ± 20 s.University of Wisconsin Milwaukee. Aug 2006 - Dec 20137 years 5 months. Milwaukee. Studied the cellular and molecular mechanisms of acquiring, updating, and maintaining memory for fear conditioning.Europe PMC is an archive of life sciences journal literature.May 26, 2016 · Graham D. L. et al. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat. Neurosci. 10, 1029–1037 (2007). [Google Scholar] Graham D. L. et al. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol. Psychiatry 65, 696–701 (2009). Janine L. Kwapis, Timothy J. Jarome, Mary E. Lonergan, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 72 Citations (SciVal) Overview; Fingerprint; Abstract. Recent work on the long-term stability of memory and synaptic plasticity has identified a potentially critical role for protein kinase ...Janine L. Kwapis, Yasaman Alaghband, Ashley A. Keiser, Tri N. Dong, Christina M. Michael, Diane Rhee, Guanhua Shu, Richard T. Dang, Dina P. Matheos, Marcelo A. WoodThe emphasis here is on the lines available as opposed to methods on how to develop transgenic mice, which has been discussed in detail previously (Doyle et al., 2012). Additionally, we will discuss other genetic tools available to neuroscientists, such as siRNAs, viral-mediated approaches, and variations of the CRISPR-Cas9 system.Trace fear conditioning, in which a brief empty " trace interval" occurs between presentation of the CS and UCS, differs from standard delay conditioning in that contributions from both the hippocampus and prelimbic medial prefrontal cortex (PL mPFC) are required to form a normal long term memory.L, Quantification of compound action potentials above the lesion (mean ± SEM, One-way ANOVA, Fisher's LSD post-hoc ***P<0.001, n = 4-7/group). The EE-dependent increase in neurite outgrowth was abolished when incubating the neurons with the transcriptional inhibitor actinomycin-D , suggesting a dependence of this response on gene ...Neurobiology of learning and memory 128, 103-109. , 2016. 114. 2016. Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. MR Gilmartin, JL Kwapis, FJ Helmstetter. Neurobiology of learning and memory 97 (4), 452-464.Janine Kwapis is an Assistant Professor of Biology at Penn State University based in University Park, Pennsylvania. Previously, Janine was a Gradu ate Student at University of Wisconsin - Milwaukee. Janine received a Ph. D. degree from University of Wisconsin-Milwaukee.Assistant Professor of Biology Department of Biology jlk855 Janine Kwapis Biography Education B.A., Psychology, Alma College M.S., Behavioral Neuroscience, University of Wisconsin-Milwaukee Ph.D., Behavioral Neuroscience, University of Wisconsin-Milwaukee Postdoc Training University of California, Irvine Research InterestsJanine L. Kwapis; Alberto J. López; André O. White; Osasumwen V. Aimiuwu; Amni Al-Kachak; Kasuni K. Bodinayake; Nicole C. Oparaugo; Richard Dang; Mariam Astarabadi; Dina P. Matheos; Marcelo A. Wood; Neurobiology of Learning and Memory. Published on 01 Nov 2017. 0 views XX downloads; XX citations; Context and Auditory Fear are …Europe PMC is an archive of life sciences journal literature.Dec 13, 2019 · Europe PMC is an archive of life sciences journal literature. International Journal of Molecular Sciences Editorial Special Issue "Molecular Mechanisms of Memory Formation and Modification" Timothy J. Jarome 1,2,* and Janine L. Kwapis 3,4,* Citation: Jarome, T.J.; Kwapis, J.L. Special Issue "Molecular MechanismsAuthor links open overlay panel Janine L. Kwapis 1, Timothy J. Jarome 2, Jonathan L. Lee, Fred J. Helmstetter. Show more. Add to Mendeley. Share. ... (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014) and have hypothesized that trace memory may be stored in a distributed cortical network that includes prelimbic and retrosplenial cortices ...How to say Janine L Kwapis in English? Pronunciation of Janine L Kwapis with and more for Janine L Kwapis.Janine L. Kwapis Neuropsychopharmacology (2023) Mapping the spatial transcriptomic signature of the hippocampus during memory consolidationExampleOULTest Video: Video 1: ExampleOULTest.mpg. Title: Example Test session from OUL for scoring practice. This video is from an OUL test session with four young male C57BL/6J male mice run simultaneously. Two of these animals (the top right and bottom right boxes) were “No Update” animals and two animals each received a …Dr. Diane Rhee, MD is a psychiatrist in New York, New York. Dr. Rhee is on Doximity. As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.Janine L. Kwapis, Ph.D., Department of Biology, Penn State University Public Neuroscience Seminar; Wednesday, December 4th, 2019; 11:00 am – 12:00pm; Fralin Auditorium; Aging is accompanied by impairments in both long-term memory and circadian rhythmicity.If updating can reorganize the trace memory so that it relies on the delay circuit, after the memory restabilizes, the amygdala should be required for extinction (Kwapis et al, 2014a) and the RSC should no longer be involved in memory retrieval (Kwapis et al, 2014a; Kwapis et al, 2015b). Thus, we can test whether reconsolidation-dependent ...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA Corresponding author: fjh{at}uwm.edu Abstract The extinction of …Janine L. Kwapis, Timothy J. Jarome, Jonathan L. Lee, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 66 Scopus citations. ... of two cues separated by an empty period of time. We have previously shown that trace fear extinction requires the RSC (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter ...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA ... (NIMH) grants R01MH069558 to F.J.H. and NIMH grant F31MH090685 to J.L.K. We thank Marieke R. Gilmartin and Jonathan L. Lee for technical assistance. Previous Section Next Section ...Chad W. Smies a, Janine L. Kwapis a, ∗ a Department of Biology, Pennsylvania State University, University Park, PA b Department ofNeurobiology and Behavior, University California, Irvine, CA a r t i c l e i n f o Article Aginghistory: both Received 17 October 2022 Revised 3 February 2023 Accepted 18 February 2023 Available online 23 February ...Janine L. Kwapis Valeria Lallai Michael S. Landy Fiona E. N. LeBeau Jae K. Lee Christian H. Lemon Janna D. Lendner Tylor R. Lewis Ya Dong Li Kyle P. Lillis Taosheng Liu Daniel A. Llano Hanbing Lu Heiko J. Luhmann Bryan W. Luikart Carl R. Lupica ...Alzheimer's Disease affects 5.4 million Americans [1] and by 2030, approximately 13.8 million people 65 or older are projected to have the disease [2]. Even more individuals will experience normal age...Janine L. Kwapis. Janine L. Kwapis. Scilit Preprints.org Google Scholar * Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USA * Author to whom correspondence should be addressed.Nicole C. Ferrara 1,2 Janine L. Kwapis 3 Sydney Trask 4,5* 1 Discipline of Physiology and Biophysics, Rosalind Franklin University, North Chicago, IL, United States; ... Gilmartin, M. R., Kwapis, J. L., and Helmstetter, F. J. (2012). Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ...Janine L. Kwapis, Timothy J. Jarome, Nicole C. Ferrara, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 17 Scopus citations. Overview; Fingerprint; Abstract. Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work has shown ...Janine Kwapis. Pennsylvania State University; Show all 11 authors Hide. ... activation, and that BDNF rescues theta-L TP and cocaine-associated memory deficits in. BAF53b transgenic mice.Normal aging is accompanied by cognitive impairments, most notably disruptions in memory formation and updating, the ability to incorporate new information into existing memory. As lifespans increase...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA ... (NIMH) grants R01MH069558 to F.J.H. and NIMH grant F31MH090685 to J.L.K. We thank Marieke R. Gilmartin and Jonathan L. Lee for technical assistance. Previous Section Next Section ...PDF | On Mar 26, 2012, Marieke R Gilmartin and others published Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or ...Alberto J López 1 , Enikö Kramár 1 , Dina P Matheos 1 , André O White 1 , Janine Kwapis 1 , Annie Vogel-Ciernia 2 , Keith Sakata 1 , Monica Espinoza 1 , Marcelo A Wood 3 Affiliations 1 Department of Neurobiology and Behavior and Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92697 ...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA; Corresponding author: fjh{at}uwm.edu; Abstract. The extinction of delay fear conditioning relies on a neural circuit that has received much attention and is relatively well defined. ...Kwapis JL, Jarome TJ, Gilmartin MR, Helmstetter FJ. Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. Neurobiol Learn Mem. 2012; 98:148–153. doi: 10.1016/j.nlm.2012.05.003. [PMC free article] [Google Scholar] Epigenetic mechanisms result in persistent changes at the cellular level that can lead to long-lasting behavioral adaptations. Nucleosome remodeling is a major epigenetic mechanism that has not been well explored with regards to drug-seeking behaviors. Nucleosome remodeling is performed by multi-subunit complexes that interact with DNA or chromatin structure and possess an ATP-dependent enzyme ...BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens André O. White, Enikö A. Kramár, Alberto J. López, Janine L. Kwapis, John Doan, David Saldana, M. Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P. Matheos and Marcelo A. Wood () ...Nicole C. Ferrara 1,2 Janine L. Kwapis 3 Sydney Trask 4,5* 1 Discipline of Physiology and Biophysics, Rosalind Franklin University, North Chicago, IL, United States 2 Center for Neurobiology of Stress Resilience and Psychiatric Disorders, Rosalind Franklin University, North Chicago, IL, United StatesJanine Kwapis Assistant Professor, Biology h-index 1482 Citations 24 h-index 2009 2023 Research activity per year Overview Fingerprint Network Grants & Projects (4) Research …The past decade has produced an explosion in the number and variety of genetic tools available to neuroscientists, resulting in an unprecedented ability to precisely manipulate the genome and epigenome in behaving animals.Finally, Bellfy and Kwapis review the evidence that the reconsolidation process may allow existing memories to update in response to new, relevant information . In their review, the authors outline the major behavioral paradigms used to study reconsolidation and describe the different molecular mechanisms across the brain that …Destiny S. Wright, 1 Kasuni K. Bodinayake, 1 and Janine L. Kwapis 1, * Destiny S. Wright 1 Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, USAJanine L. Kwapis, Department of Neurobiology and Behavior, Ayala School of Biological Sciences, University of California, Irvine, CA, USA. UC Irvine Center for Addiction Neuroscience, Ayala School of Biological Sciences, University of California, Irvine, CA, USA. Search for more papers by this author.Christopher W. Butler, Ashley A. Keiser, Janine L. Kwapis, Nicole C. Berchtold, Vanessa L. Wall, Marcelo A. Wood, Carl W. Cotman; Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity; Learn Mem. 2019 Dec; 26(12): 485-492. ... Daniel L. Gillen, Pierre Baldi, David A. Bennett, Aron S. Buchman ...Jarome, Timothy J. ; Kwapis, Janine L. / Special issue "molecular mechanisms of memory formation and modification ...Janine L. Kwapis and Marcelo A. Wood Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA Post-traumatic stress disorder (PTSD) and other anxiety disorders stemming from dysregulated fear memory are problematic and costly. Understanding the molecular mechanismsThe circadian clock plays a prominent role in neurons during development and throughout aging. This review covers topics pertinent to the role of 24-h rhythms in neuronal development and function, and their tendency to decline with aging. Pharmacological or behavioral modification that augment the function of our internal clock may be central to decline of cognitive disease and to future ...Janine L Kwapis; Timothy J Jarome; Nicole C Ferrara; Fred J Helmstetter; Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work ... | Cgilwlc (article) | Mdluhyqq.